Objective: The aim of the study is to conduct a statistical survey among 49 psychiatrists in order to explore the most common pharmacological approaches used in clinical practice for the treatment of Bipolar Disorder (BD) and the occurrence and the management of the related unwanted effects.

Materials and Methods: The survey was conducted by using a Google Form.

Results: The collected results reveal that valproic acid is the most used treatment, aiming to stabilize patients’ mood keeping it in a balanced range. However, this pharmacological therapy may expose patients to several adverse effects that can worsen their quality of life and adherence to the therapy.

Conclusions: Clinicians commonly use valproic acid in clinical practice and most of them do not intervene on the management of the related side effects, considering them as part of the therapy. Therefore, considering both the lack of strategies for counteracting adverse effects in medical practice and Myo-Inositol positive effect on reported pathological conditions, a concomitant supplementation with Myo-Inositol may be suggested in the management of these patients.